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In autoimmune diseases such as lupus, rheumatoid arthritis, and multiple sclerosis, chronic inflammation and oxidative stress can damage tissues and interfere with immune tolerance

Resveratrol induces glutathione synthesis and protects against oxidative stress

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Thermo Fisher Scientific) at 37C for 30 min, followed by DNase inactivation with 4.5 mM EDTA at 65C for 10 min