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This study used both RUCAM analysis as well as expert opinion for a combined evaluation of each patient case to determine the likelihood of causality
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Dosage ranges reflect clinical protocols used at our Doral clinic and should not be applied without a medical consultation
Although current guidlines mainly recommend SGLT-2 inhibitors and GLP-1 RAs to be served as first-line drugs to T2DM patients with high cardiovascular risks due to their proven cardiovascular benefits, effects of metformin on MACE still remain potential and dubious according to ADA 2023
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