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Much of the reason that so many thyroid patients continue to suffer from hypothyroid symptoms, including cold intolerance, is that many thyroid patients remain undertreated despite taking thyroid medication

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Thus, these comorbid conditions may further exacerbate the proinflammatory endothelial and monocyte phenotypes associated with preexisting G6PD-d, thereby compounding CVD risk 28,29,30

That is modest versus Zepbound (~21%) or Wegovy (~15%)

The most commonly reported side effect is gastric distress when higher doses of NAC were given