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Although none of the ELISA kits marketed for mBDNF showed complete specificity for this isoform, the human free BDNF Quantikine ELISA kit (#DBD00, R&D Systems) was the unique assay that measured mature BDNF with an acceptable specificity and may serve as a suitable option for estimating serum mBDNF levels

The data from this registry demonstrates a survival advantage associated with intravenous A1AT administration, which develops independently and decoupled from the FEV1 decline (67)

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