Organelle-specific mechanisms in crosstalk between apoptosis and ferroptosis
Notably, ammonia is simultaneously generated as a byproduct of glutamine deamination
Abbreviations AD: Alzheimer disease A: Amyloid beta CI: Confidence interval DSM: Diagnostic and Statistical Manual of Mental Disorders DTBN: 5,5-Dithio-bis(2-nitrobenzoic acid) GSH: Glutathione HC: Healthy control MCI: Mild cognitive impairment MEGA-PRESS: Meshcher-Garwood Point-Resolved Spectroscopy MMSE: Mini-Mental State Examination MRS: Magnetic resonance spectroscopy OPA: O-Phthalaldehyde OS: Oxidative stress PRESS: Point resolved spectroscopy SMD: Standardized mean difference STEAM: STimulated Echo Acquisition Mode References Koyama A, O'Brien J, Weuve J, Blacker D, Metti AL, Yaffe K
Noval advance of histone modification in inflammatory skin diseases and related treatment methods
Knocking down ACTL6A expression with shACTL6A significantly reduced tumor growth, and NAC treatment (intraperitoneal (i.p.) injection, 200 mg/kg/day) significantly reversed this effect (Fig