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Steady state is reached in 4 to 5 weeks of weekly dosing at each dose level -- which is why the standard titration holds each dose for 4 weeks before escalating

10.1016/j.biomaterials.2020.120278 82 ZhangM.GuoX.WangM.LiuK

also identified as SOD3)

J Neurosci 34, 1351613534 (2014)

Am J Physiol Lung Cell Mol Physiol 294:L478488 Garg R, Gupta S, Maru GB (2008) Dietary curcumin modulates transcriptional regulators of phase I and phase II enzymes in benzo[ a ]pyrene-treated mice: mechanism of its anti-initiating action

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