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analyzed patients initially treated with GLP-1 RAs or SGLT2i, subsequently adding the second agent to evaluate the effects of combination therapy compared to monotherapy and differencing across groups (113, 114)

Side Effects and How They Are Managed Side effects of Qsymia may include dry mouth, mild tingling sensations, altered taste, constipation, or difficulty sleeping if taken too late in the day

Its discovery traces back over 150 years to research on glucosuria ( By blocking sodium-glucose cotransporter 2 in the S1 and S2 segments of the proximal tubule, SGLT2i significantly reduce glucose reabsorption, promoting urinary glucose excretion