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Stronger bones A B12 deficiency can lead to osteoporosis, brittle bones, and fractures

Shortages prompted an EMA alert in March 2024, leading to rationing protocols prioritizing cardiovascular co-morbid patients

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The SDUD is publicly available data provided as part of the Medicaid Drug Rebate Program (MDRP), and provides information on the number of prescriptions, Medicaid spending before rebates, and cost-sharing for rebate-eligible Medicaid outpatient drugs by NDC, quarter, managed care or fee-for-service, and state

Some protocols recommend gradual titration up to 20 to 45 mg per day if no significant side effects appear