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With a growing body of research supporting its efficacy, GLP-1 offers hope for those seeking sustainable and effective weight loss solutions

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These effects have been demonstrated in cell cultures, animal models, and limited human studies

Potential areas of expansion include: Cardiovascular outcomes: A dedicated CVOT, if not already required as a post-marketing commitment, would evaluate whether orforglipron reduces MACE in patients with established cardiovascular disease or high cardiovascular risk, following the precedent set by the SELECT trial for semaglutide