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doi: 10.1073/pnas.1817391116 69 PerryTHaugheyNJMattsonMPEganJMGreigNH

What to do when you're hungry Why

To help, Pharmacy Benefits Managers (PBMs) should have options to curb spending for their clients, particularly on medications for which lower-cost alternatives are readily available

Doctors may increase your GLP-1 dose if weight loss plateaus, hunger returns, or initial side effects subside

It is typically characterized by early onset (in childhood and adolescence), more pronounced weight gain, higher body fat percentage, and more severe hyperphagia, often accompanied by endocrine disorders (such as hypogonadism)