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The price reflects the brand name and FDA-approved formulation

In the push for coverage, the Director of the Department of Health and Human Services (DHHS) expressed that the drugs are phenomenal and that I believe that theyre being held back from the people of North Carolinawhen they could be promoting a great deal of value here in the buckle of the Barbecue Belt. The director also explained to lawmakers that it will not cost the state more than $10 million annually because the federal government will pay for most of it

However, the accelerated approval pathway means that evidence is still interim: while part one of the ESSENCE trial demonstrated improvement in liver scarring and inflammation, it does not yet show whether semaglutide reduces the risk of serious outcomes such as cirrhosis, liver failure or liver cancer

In January 2025, the FDA approved an injectable form of semaglutide (Ozempic) specifically for managing chronic kidney disease in type 2 diabetes patients

The withdrawal pattern typically involves gradual return of appetite over 2 to 4 weeks, followed by weight regain over the subsequent months