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Research-grade drugs are less strictly monitored for contaminants, so they arent safe for humans to use

Lyophilization, capping, and labeling occur in a controlled environment, and lot-specific COAs link directly to the chromatograms produced during release testing

10.1158/1535-7163.Mct-21-0962 25 Di DonatoM.BilancioA.D'AmatoL.ClaudianiP.OlivieroM

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Melatonin synthesis was evaluated by measuring urinary 6-sulfatoxymelatonin, the primary metabolite of melatonin, which increased 1.6-fold in the Epitalon group relative to placebo