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10.1016/j.pharmthera.2012.12.007 [DOI] [PubMed] [Google Scholar] Zeng, T

Mice that are fed a high-fat diet display increased hepcidin expression in adipose tissue

In the basal state, ABHD5 is bound to PLIN1 (14, 37), which upon hormonal stimulation (described in detail below) releases ABHD5 to interact with PNPLA2 (Figure 1)

In spermatids, it is abundantly expressed as active peroxidase and during final maturation, it is transformed into a structural protein enzymatically inactive