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These development complexities contribute to substantial research and development costs, lengthy preclinical and clinical evaluation timelines, and rigorous regulatory approval requirements

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Thirty minutes later, rats were individually transported to the testing room in a clean, unused, transparent cage, on a four-wheeled cart by a different experimenter

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It is defined as weight in kilograms (kg) divided by height in meters squared (m 2 ) where a BMI of 2529.9 kg/m 2 is classified as overweight and a BMI 30 kg/m 2 is classified as obese