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To understand how a GLP-1 agonist works, it is necessary to first understand the working of a naturally existing GLP-1 hormone that our intestine releases

The intake flow is broadly consistent: questionnaire, clinician review, prescription if eligible, fulfillment, and follow-up for titration and side effects

Data from the STEP 4 trial demonstrated that discontinuation of semaglutide typically results in return of appetite and substantial weight regain, indicating that for many individuals, ongoing treatment may be necessary to maintain benefits

Regul Toxicol Pharmacology 110:104544

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