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The ADP-ribosyl transfer reactions that are of the most interest are shown in figure 5 and include: (1) cluster of differentiation 38 (CD38), (2) poly-ADP-ribose polymerases (PARPs), and (3) Sirtuin deacetylases (Sirtuins)

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Its long-term pharmacological use likely would lead to profound muscle loss

These findings can inform clinical decisions and optimising treatment strategies in the management of type 2 diabetes