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The dysesthesia reported in trials, that unusual tingling or altered touch sensation, appears primarily at these higher doses

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PubMed Systematic reviewGLP-1 class evidence2025 Effect of glucagon-like peptide-1 receptor agonists and co-agonists on body composition Supports body-composition, lean-mass, and metabolic-risk context

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For women with polycystic ovary syndrome (PCOS), a condition closely linked to insulin resistance and obesity, GLP-1-based therapies have shown some promise in improving hormonal profiles, reducing androgen levels, and restoring menstrual regularity