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The primary outcome occurred in 41/277 (semaglutide) versus 38/273 (placebo) participants on SGLT2i at baseline (hazard ratio 1.07

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Further, we reviewed how the gastrointestinal tract healing could be generally perceived (i) in terms of angiogenic growth factors, and/or (ii) through the healing of extragastrointestinal tissues healing, such as tendon, ligament, muscle and bone, and vice versa

Food and Drug Administration approved it as Mounjaro for type 2 diabetes in 2022 and as Zepbound for chronic weight management in 2023, and it is authorized by the European Medicines Agency as well

Regarding baseline medication, over 80% of participants were on statins, and 40% were taking SGLT2 inhibitors