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2.2.2 ERK1/2-HDAC6 signaling pathway The GLP-1R-ERK1/2-HDAC6 signaling pathway complements the mitophagy pathway by modulating oxidative stress and autophagy

The mRNA levels were measured employing SYBR Green PCR premix (TaKaRa, Japan)

Optimal antioxidant levels in the body have been associated with cognitive preservation, and several studies have demonstrated the neuroprotective effects of catechins, highlighting their potential as adjunctive therapy in select neurodegenerative diseases

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The peptide has been studied extensively across various organ systems, demonstrating cytoprotective effects in the gastrointestinal tract, liver, pancreas, heart, blood vessels, muscle, tendon, ligament, bone, and nervous system