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Activation of the Notch signaling pathway, a highly conserved signaling pathway in the heart, is critical for cardiomyocyte proliferation at birth and for cardiac development (118)

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However, ML-based integration still faces hurdles before its widespread implementation in multi-omics research

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Similarly, in breast cancer, LOH at this locus occurred in approximately 36% of breast cancer tissues, and GPx1 with a leucine-containing allele exhibited lower GPx1 activities in response to stimulation than GPx1 a proline-containing allele [88]