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Constipation affected 17% of Retatrutide users compared to 16% for Mounjaro

In animal research, giving Akkermansia to mice improved features of diet-induced metabolic problems (Everard et al., 2013), and a small human trial found that pasteurized Akkermansia was safe, well tolerated, and linked to some improved metabolic markers in adults with overweight or obesity (Depommier et al., 2019)

Retrieved from Vosoughi, K., Roghani, R

Could it be genetic

That's the medication working exactly as it should - tirzepatide slows gastric emptying and sends fullness signals to your brain, making it easier to eat less without feeling deprived