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In fact, an alternative explanation of hyperhomocysteinemia without a concomitant increase in GSH is as follows: Excess homocysteine is exported out of the cells to avoid toxicity, and this manifests clinically as hyperhomocysteinemia

However, it is worth noting that the optimal dose and duration of vitamin C administration may vary depending on the severity of the disease and individual patient factors

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Cardiovascular: Pulmonary edema and congestive heart failure early in treatment

Vancampfort D, Hallgren M, Mugisha J, Hert M, Probst M, Monsieur D, Stubbs B