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Huang HH, Huang HH, et al

GLP-1 medications, including tirzepatide, have been associated with this effect

No controlled trial comparing intra-articular AOD-9604 to placebo or standard intra-articular therapies (hyaluronic acid, corticosteroids) has been completed

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In terms of GLP-1 receptor agonists (plus the mixed agonist-GIP modulator single case study), this similarly showed reduction in postprandial glucose peak and more appropriate insulin peak and timing after induction the intervention which subsequently responded to improved symptoms (total 7 patients) [29, 30]