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Chronic gut permeability is where it becomes a problem LPS crossing into the bloodstream can get past the blood-brain barrier too When it does, it activates microglia (the brains immune cells) which start breaking down the blood-brain barrier

Xu C, Sun L, Ren F, et al

M., Estes, M

Compared to age- and sex-matched individuals in the general population, patients with schizophrenia have a roughly 50% higher risk of dying from cancer (Nordentoft et al., 2021), with seven quantitative studies of 1,162,971 participants yielding mortality risk from breast, colon, lung, and prostate cancer (Ni et al., 2019)

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