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Signs of Correct Administration A successful B12 injection should cause: Minimal pain at the site A small bump that fades within an hour Mild redness or soreness that resolves within 24 hours If symptoms worsen (swelling, pain, fever, rash), consult a doctor immediately

doi: 10.1016/s0140-6736(19)31149-3

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This profound demographic shift marks the advent of a new era characterized by population aging [3,4,5].Meanwhile, global average life expectancy has risen from 46.5 years in 1950 to 71.7 years in 2022, and is projected to reach 77.3 years by 2050 [2]