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The aim of using Tretinoin and Hydroquinone is to combine pigment suppression with increased turnover

Mitochondrial dysfunction has been recently proposed as a key pathophysiological mechanism [3] linked to processes commonly found in depression, including neurotoxicity, impaired neuroplasticity, inflammation and insulin resistance [2,3,4,5]

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Studies show it typically leads to about a 4% drop in body weight over six months