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186 However, T cells have a mechanism to combat arginine deficiency: when confronted with arginine deficiency caused by Arg1-expressing myeloid cells, T cells increase arginine biosynthesis by up-regulating ASS1 expression

Conjugation with glucuronic acid: Glucuronic acid is available from glucose and its conjugation with lipid-soluble drugs results in a lipophilic glucuronic acid derivative which is typically pharmacologically inactive and more water-soluble compared to the parent compound

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Multiple drug combinations have several advantages over monotherapy, as they can achieve higher efficacy and, by using lower drug doses, reduce the risk of adverse effects and acquired resistance (25)

Success depends on follicle viability