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Abstract Gouty arthritis (GA), a condition characterized by monosodium urate (MSU) crystal deposition and NLRP3 inflammasome-driven inflammation, is a result of a complex interplay between hyperuricemia and immune dysregulation, which leads to systemic complications and joint damage

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Information sources We searched PubMed, Embase and Cochrane databases on 27 October 2021 for English-language studies