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Injectable peptides are 5-7 times more potent than oral, but you are free to choose whichever option you feel most comfortable with

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Specific triggers for medical consultation include achieving less than 5% body weight reduction after reaching the maintenance dose (for Wegovy, after 12 weeks at 2.4 mg as per FDA labeling), prolonged weight loss plateau despite adherence, or intolerable side effects preventing dose escalation to therapeutic levels

Once-weekly injectable formulations such as semaglutide and dulaglutide can be administered at any time of day, provided consistency is maintained