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It supports angiogenesis, the blood vessel formation that supplies healing tissues

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Over 50% of CM cases report activating mutation of the BRAF gene (79), while merely 16% of MMs experience the same alteration ( BRAF is distinct from NRAS in MM in that the locus undergoes amplification in 13% of cases ( BRAF gene are missense mutations and they most frequently occur at codon 600, the activating loop, where amino acids change from valine to glutamic acid (V600E) (93)

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