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Similarly, IGF-1, which is homologous to insulin and has partial common receptor affinity, can activate post-receptor signaling in neurons to ameliorate diabetic neuropathy (50)

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If the expectation is immediate pain elimination without behavior change, the protocol will disappoint

For example, administration of recombinant CuZnSOD to premature infants attenuated inflammation, with subsequent improvement in clinical outcomes in later stages of life

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