Reuben A, Tillman H, Fontana RJ, Davern T, McGuire B, Stravitz RT, Durkalski V, Larson AM, Liou I, Fix O, Schilsky M, McCashland T, Hay JE, Murray N, Shaikh OS, Ganger D, Zaman A, Han SB, Chung RT, Smith A, Brown R, Crippin J, Harrison ME, Koch D, Munoz S, Reddy KR, Rossaro L, Satyanarayana R, Hassanein T, Hanje AJ, Olson J, Subramanian R, Karvellas C, Hameed B, Sherker AH, Robuck P, Lee WM
Gastrointestinal discomfort, a common reason for discontinuation, can often be managed by starting with a lower dose, gradually increasing it, or taking the medication with food
Gradual Dose Escalation MWLI physicians titrate dose slowly typically over 1620 weeks to minimize side effects while maximizing fat loss
Most people report feeling dramatically better within an hour, which beats suffering through a day-long hangover
According to FDA labeling, these medications are not recommended for patients with severe gastroparesis or severe gastrointestinal disease