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How do these compounds compare to semaglutide

Bacteriostatic water = sterile water + 0.9% benzyl alcohol The added benzyl alcohol acts as a preservative, so a single reconstituted vial can be drawn from repeatedly instead of needing to be used all at once

But this enhanced potency also means that dosing strategy is more critical than ever

Some of the agents have also been shown to reduce the risk of major adverse cardiovascular events such as cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke

MSDC-0602K has shown substantial decreases in glucose, insulin, liver enzymes, and the non-alcoholic fatty liver disease activity score (NAS) in patients with biopsy-confirmed MASH and fibrosis (F1-F3) with minimal side effects, 21 prompting a phase 3 study to assess the benefits of MSDC-0602K on glycemic control and cardiovascular outcomes in patients with pre-T2D or T2D and MASLD/MASH (NCT03970031)