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Immunofluorescence staining of Ki67, a marker for proliferating cells, was used to assess the proliferation of human umbilical vein endothelial cells (HUVECs) 63

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A small retrospective study in the 1980s reported increased placental copper concentrations in 8 preeclamptic women compared to 10 controls (53 versus 124 g/Kg, resp.), suggesting that this increase in preeclampsia maybe an exaggerated response of normal pregnancies [92]

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