What to know about weight-loss drugs before trying to conceive Fact checked by Jim Lacy Many women are turning to popular injectable medications, glucagon-like peptide-1 (GLP-1) agonists, to control blood sugar and body weight
According to a systematic review of five randomized controlled trials presented at ENDO 2026, GLP-1 drugs do not harm male hormones, sexual function, or sperm quality with long-term use
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Interestingly, preconception administration of liraglutide 1.2 mg and metformin was associated with increased pregnancy rate per embryo transfer and cumulative pregnancy rate in women with obesity in PCOS compared to metformin monotherapy, despite similar weight reduction 98