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The risk-benefit profile of triple agonists remains under investigation

In a series of recent studies, we found that mitochondrial function in white adipocytes is essential to the synthesis of adiponectin, which is the most abundant adipokine synthesized from adipocytes, with many favorable effects on metabolism, including improvement of insulin sensitivity and reduction of atherosclerotic processes and systemic inflammation

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It is expressed exclusively in testes, kidney, and intestine and has the highest specificity for carnitine [14]