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Research has shown reductions in C-reactive protein and other inflammatory markers in patients on semaglutide and tirzepatide that exceed what weight loss alone would explain

2008 Jan/Feb;73(1):R14-R19

The delay in gastric emptying is dose-dependent but is attenuated with the recommended dose escalation to higher doses of TRULICITY [see Dosage and Administration (2.1), Drug Interactions (7.1)]

16 The effect was large enough to matter clinically, not just statistically