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Proportional Muscle Loss: The percentage of weight lost from lean mass is practically identical between the two drugs

SURMOUNT-5 is the only direct head-to-head trial among the three

Fasting insulin, C-peptide, and HOMA2-IR fell by as much as 50 percent or more

GLP-1 medications reduce food intake, which means less fiber and less water from food

The FDA Approval Timeline: A Realistic Outlook Projecting FDA approval dates involves several variables that are partially opaque to outside observers, including trial completion dates, data lock, NDA submission timing, and the FDA's review clock

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