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ASI CGMP CERTIFICATION

2018, Feb, 6;90(3):203140 Dunn WB, Broadhurst D, Begley P, Zelena E, Francis-McIntyre S, Anderson N, et al

In GA-1, the body produces high levels of two specific substances: glutaric acid and 3-hydroxyglutaric acid [3]

Phlorizin, a flavonoid glycoside, alleviated visceral hypersensitivity by inhibiting sodium/glucose cotransporter 1 (SGLT1) expression and blocking corticotropin-releasing factor- and lipopolysaccharide (LPS)-induced epithelial permeability, indirectly supporting gut-brain homeostasis

8,11 The protein adducts formed, specifically those of mitochondrial protein adducts, lead to oxidative injury and hepatocellular necrosis