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We used the contour-enhanced funnel plots to assess publication bias, if 10 or more trials were available for an outcome (Harbords test for dichotomous outcomes and Eggers test for continuous outcomes) [23, 24]

Do not treat XR tablets as a substitute for immediate-release tablets unless your clinician specifically changes the formulation

This aligns with mechanistic studies showing that dipyridamole dampens aberrant monocyte/macrophage activation and may protect against progression to clonal hematopoiesis or histiocytic disorders

But it can easily overshoot, or even choose targets seemingly without reason