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Apoptosis Induction: This triggers the caspase cascade, leading to the apoptosis (death) of the endothelial cells lining the blood vessels

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4 The role of the endothelial cell glycocalyx in sepsis 4.1 Early damage and the vicious circle of endothelial glycocalyx pathology in sepsis Sepsis is a systemic disease, but the vascular endothelium is the first site that is exposed to bacterial endotoxin