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As other Rho GTPases [48,49], Sept2 is crucially involved in modeling neurite outgrowth during neuronal differentiation and a tight regulation of its expression is necessary [50]

It is a naturally occurring substance in the body, composed of three essential amino acids: cysteine, glycine and glutamic acid

CGRP binds to CLR receptors on osteoblast cell surfaces, directly enhancing osteogenic gene expression

Some patients require titration to a strength between commercially available options, or need a starting dose lower than the lowest commercial product offers

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