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With respect to liver fibrosis, MenSCs secrete an array of factors that collectively form a synergistic paracrine network

Individuals carrying certain alleles may experience more pronounced appetite suppression, faster energy utilization, or altered satiety signalingincreasing fatigue risk during early treatment or aggressive dose escalation

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In contrast, the effect on lean mass was minor and not significant relative to vehicle control (Supplemental Figure 1)

Our findings expand the current knowledge of microbiota-BA interaction, and provide evidence that HZRG administration reduces pathogenic microbiota, enhances fecal BA excretion, and reduces secondary BA accumulation in the intestine