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This research suggests that while curcumin remains a promising nutraceutical for skin health, more studies examining oral formulations in aging populations are needed to establish optimal dosing and delivery methods for skin health benefits

Arch Biochem Biophys (2022) 727:109347

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An imbalance of estrogen and testosterone in women can cause breast tenderness, low sex drive, mood swings, irregular periods, worse PMS symptoms, weight gain, weight loss resistance, hair loss, headaches, endometriosis, polycystic ovarian syndrome (PCOS), and thyroid disorders

The article specifically warns against relying on online sources that call the combination risk-free