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The peptide includes modifications that resist DPP-IV degradation
3,5 Minimum safe caloric floors must be respected
So, pharmaceutical companies started investigating the use of GLP-1s for weight-management purposes, and the first GLP-1 weight-loss drug, Saxenda (liraglutide), was approved by FDA in 2014 (it was previously approved to treat diabetes under the name Victoza)
The goal is to use these medications to buy time while helping patients implement sustainable lifestyle changes, she says
By enhancing gut-brain signaling , these drugs help: Control appetite Stabilize blood sugar Calm immune over-activation Support healthy gut flora This gut-metabolic connection explains why people using GLP-1 drugs often report better digestion, improved mood, and higher energy
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