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Enhanced Skin Pigmentation: Known as a melanocortin receptor agonist, United States in vivo studies show it binds to melanocortin receptors in melanocytes, stimulating the production of eumelanin, the pigment responsible for skin color

It is also important to take into account the nuclear expression of NTRK, which is more common in Spitz tumors with NTRK3 fusions than in those with NTRK1 fusions

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