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Finally, reduced excitotoxicity and improved overall handling of glutamate could be achieved through improved metabolism (e.g., increased ATP production) in astrocytes, which are responsible for the uptake of glutamate from the synaptic cleft (113)

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It also promotes environmental responsibility, preventing used needles from posing a hazard to others

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The Panel conceptualized potential AEs in terms of severity, duration and reversibility

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