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Regarding thyroid effects: preclinical studies in rodents have identified C-cell changes with GLP-1 receptor agonists, though the relevance of these findings to humans has not been established

Retatrutide: Single-molecule triple agonist targeting GIP, GLP-1, and glucagon receptors simultaneously

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Peptide hormones, growth factors, related substances, and mimetics, S4

Ozempic (semaglutide) and Mounjaro (tirzepatide) These are FDA approved for type 2 diabetes, not for weight loss