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An interesting pharmacological aspect of proteolytic enzymes, particularly bromelain, is their dual functionality based on when they are consumed

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We also used MetaboAnalyst v5.0 (Xia Lab @ McGill University, Montreal, QC, Canada) [30] to identify the metabolites that contribute to group separation using Partial Least Squares-Discriminant Analysis (PLS-DA), heat map, and pathway analysis

Funding This work was supported by the National Science and Technology Major Project (2022ZD0117700), the National Natural Science Foundation of China (32270759) and the Research Foundation for Postdoctoral (AUGA5710026124)