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Two transgenic mouse lines were established using the lac -operon system, the HD LacO -MGF transgenic mouse (referred as M mice) and Lac I transgenic mouse (referred as R mice) (Fig

10.1530/EC-19-0449 59 JinnoM.NagaiR.TakeuchiM.WatanabeA.TeruyaK.SugawaH.et al (2021)